A treatment for brain infarction targeting HMGB1
نویسندگان
چکیده
منابع مشابه
Targeting HMGB1 in the treatment of sepsis.
INTRODUCTION Sepsis refers to the host's deleterious and non-resolving systemic inflammatory response to microbial infections and represents the leading cause of death in the intensive care unit. The pathogenesis of sepsis is complex, but partly mediated by a newly identified alarmin molecule, the high mobility group box 1 (HMGB1). AREAS COVERED Here we review the evidence that support extrac...
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ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 2009
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.134.271